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Description

The mechanism(s) mediating the antiemetic actions of GIPR agonism are not known, despite recent work describing the phenotype of GIPR-expressing neurons in the various CNS nuclei involved in the control of energy homeostasis, including the AP and NTS (60,61)

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It reduces appetite and slows gastric emptying through a single receptor pathway

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Mobile phase B was 90% acetonitrile with 10 mM ammonium acetate, 0.1% ammonium hydroxide and 0.1% medronic acid

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doi:10.1038/cdd.2010.80

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Smoking history could be evidence of oxidative stress and an impaired oxidant defense system

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